PCR primers are used to amplify a particular STR, and the PCR product is then subjected to electrophoresis. ![]() These are repetitive sequences of DNA that are highly variable between people. When DNA first began to be used as evidence in 1988, forensic scientists combined the techniques of restriction fragment length polymorphisms (RFLP, remember rif lips?) with Southern blot to look for similarities in DNA sequences.Īn even more sensitive technique has been developed using short tandem repeats (STR). ![]() Every person has a unique genetic profile, and this fact can be exploited to confirm or rule out a suspect when compared to the profile created by the DNA left at the crime scene.Īs DNA technologies improve, so do forensic applications. Blood typing can be performed and may eliminate a suspect, but blood types are nowhere near as unique as an individual's DNA. If investigators are lucky, blood or bodily fluid may be left at a crime scene. Lucky for Team Science, these TV shows have also been useful in altering the stereotype of white-coat-wearing scientists. Although they aren't always 100% accurate in their portrayal, DNA forensic analysis has been immensely useful in solving crimes. ![]() After all, you'll learn a little about biology just by watching, right?ĬSI and similar programs have made forensics a part of pop culture. You really should finish studying for your biology exam, but you just can't tear yourself away from the latest episode of CSI.
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